Skip to main content
The Journal of Experimental Medicine logoLink to The Journal of Experimental Medicine
. 1951 Jul 1;94(1):65–71. doi: 10.1084/jem.94.1.65

THE SPARING EFFECT OF COXSACKIE VIRUS INFECTION ON EXPERIMENTAL POLIOMYELITIS

Gilbert Dalldorf 1
PMCID: PMC2136092  PMID: 14850636

Abstract

Young mice infected with Group B Coxsackie virus were rendered markedly resistant to poliomyelitis virus given from 4 to 10 days later. A sparing effect was detectable in somewhat older mice and in young mice inoculated with poliomyelitis after shorter intervals, but in both cases few mice survived. Interference was manifest by survival, by prolongation of the course of poliomyelitis, and by a decreased frequency of poliomyelitis.

Full Text

The Full Text of this article is available as a PDF (320.8 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dalldorf G., Douglass M., Robinson H. E. THE SPARING EFFECT OF DOG DISTEMPER ON EXPERIMENTAL POLIOMYELITIS. Science. 1937 Feb 12;85(2198):184–184. doi: 10.1126/science.85.2198.184. [DOI] [PubMed] [Google Scholar]
  2. Dalldorf G., Sickles G. M. An Unidentified, Filtrable Agent Isolated From the Feces of Children With Paralysis. Science. 1948 Jul 16;108(2794):61–62. doi: 10.1126/science.108.2794.61. [DOI] [PubMed] [Google Scholar]
  3. MELNICK J. L., KAPLAN A. S. Dual antibody response to coxsackie and poliomyelitis viruses in patients with paralytic poliomyelitis. Proc Soc Exp Biol Med. 1950 Aug;74(4):812–815. doi: 10.3181/00379727-74-18057. [DOI] [PubMed] [Google Scholar]
  4. MELNICK J. L., KRAFT L. M. Differentiation of immunological types among the Coxsackie viruses. Fed Proc. 1950 Sep;9(3):585–591. [PubMed] [Google Scholar]
  5. MELNICK J. L., LEDINKO N. Ohio strains of a virus pathogenic for infant mice, Coxsackie group; simultaneous occurrence with poliomyelitis virus in patients with summer grippe. J Exp Med. 1950 Feb;91(2):185–195. doi: 10.1084/jem.91.2.185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. MELNICK J. L., SHAW E. W., CURNEN E. C. A virus isolated from patients diagnosed as non-paralytic poliomyelitis or aseptic meningitis. Proc Soc Exp Biol Med. 1949 Jul;71(3):344–349. doi: 10.3181/00379727-71-17186. [DOI] [PubMed] [Google Scholar]

Articles from The Journal of Experimental Medicine are provided here courtesy of The Rockefeller University Press

RESOURCES