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. 1956 May 1;103(5):545–552. doi: 10.1084/jem.103.5.545

STUDIES ON NON-PRECIPITATING ANTIBODY

II. CIRCULATING ANTIBODY-ANTIGEN COMPLEX FOLLOWING REPEAT INJECTIONS OF ANTIGEN

Ludwig A Sternberger 1
PMCID: PMC2136630  PMID: 13319577

Abstract

Reinjection of antigen into immunized rabbits usually results in an immediate increase of circulating antibody-antigen complex. This immediate formation of complex seems to depend upon the presence of non-precipitating antibody before reinjection. The complex disappears by the 2nd day after reinjection and reappears between the 4th to 7th day. This is earlier than its first appearance after a primary injection and may indicate an anamnestic response of the non-precipitating antibody responsible for the formation of circulating antibody-antigen complex.

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Selected References

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