Abstract
A tetradecapeptide renin substrate having a biological activity comparable to the natural product and similar chemical properties has been synthesized by means of the carbobenzyloxyl azide and mixed anhydride methods.
Full Text
The Full Text of this article is available as a PDF (948.7 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Braun-Menendez E., Page I. H. Suggested Revision of Nomenclature--Angiotensin. Science. 1958 Jan 31;127(3292):242–242. doi: 10.1126/science.127.3292.242-a. [DOI] [PubMed] [Google Scholar]
- ELLIOTT D. F., PEART W. S. Amino-acid sequence in a hypertensin. Nature. 1956 Mar 17;177(4507):527–528. doi: 10.1038/177527a0. [DOI] [PubMed] [Google Scholar]
- KAHN J. R., SKEGGS L. T., Jr, SHUMWAY N. P., WISENBAUGH P. E. The assay of hypertensin from the arterial blood of normotensive and hypertensive human beings. J Exp Med. 1952 Jun;95(6):523–529. doi: 10.1084/jem.95.6.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LEVY A. L., GESCHWIND I. I., LI C. H. Corticotropins (ACTH). II. Amino acid composition of alpha-corticotropin. J Biol Chem. 1955 Mar;213(1):187–196. [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, KAHN J. R., LENTZ K., SHUMWAY N. P. The preparation, purification, and amino acid sequence of a polypeptide renin substrate. J Exp Med. 1957 Sep 1;106(3):439–453. doi: 10.1084/jem.106.3.439. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, KAHN J. R., MARSH W. H. A method of assaying small amounts of hypertensin. Lab Invest. 1953 Mar-Apr;2(2):109–114. [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, KAHN J. R., SHUMWAY N. P. The isolation and assay of hypertensin from blood. J Exp Med. 1952 Mar;95(3):241–246. doi: 10.1084/jem.95.3.241. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, KAHN J. R., SHUMWAY N. P. The preparation and function of the hypertensin-converting enzyme. J Exp Med. 1956 Mar 1;103(3):295–299. doi: 10.1084/jem.103.3.295. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, KAHN J. R., SHUMWAY N. P. The purification of hypertensin II. J Exp Med. 1956 Mar 1;103(3):301–307. doi: 10.1084/jem.103.3.301. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, LENTZ K. E., KAHN J. R., SHUMWAY N. P., WOODS K. R. The amino acid sequence of hypertensin. II. J Exp Med. 1956 Aug 1;104(2):193–197. doi: 10.1084/jem.104.2.193. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, MARSH W. H., KAHN J. R., SHUMWAY N. P. Amino acid composition and electrophoretic properties of hypertensin I. J Exp Med. 1955 Oct 1;102(4):435–440. doi: 10.1084/jem.102.4.435. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, MARSH W. H., KAHN J. R., SHUMWAY N. P. The existence of two forms of hypertensin. J Exp Med. 1954 Mar;99(3):275–282. doi: 10.1084/jem.99.3.275. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., Jr, MARSH W. H., KAHN J. R., SHUMWAY N. P. The purification of hypertensin I. J Exp Med. 1954 Oct 1;100(4):363–370. doi: 10.1084/jem.100.4.363. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SKEGGS L. T., KAHN J. R., SHUMWAY N. P. The isolation of hypertensin from the circulating blood of normal dogs with experimental renal hypertension by dialysis in an artificial kidney. Circulation. 1951 Mar;3(3):384–389. doi: 10.1161/01.cir.3.3.384. [DOI] [PubMed] [Google Scholar]