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. 1960 Jul 1;112(1):97–105. doi: 10.1084/jem.112.1.97

A MECHANISM OF THE GLYCOGENOLYTIC ACTION OF BACTERIAL ENDOTOXIN

Jay P Sanford 1, Jack A Barnett 1, Cora Gott 1
PMCID: PMC2137213  PMID: 13746229

Abstract

These experiments have demonstrated that liver glycogen may rise or fall after endotoxin administration, depending upon the antecedent diet and that total adrenalectomy followed by corticosteroid replacement abolishes the glycogenolytic effect of sublethal doses of endotoxin. It is concluded that the derangements of carbohydrate metabolism observed following the administration of sublethal quantities of bacterial endotoxin represent, not a direct hepatotoxic effect of endotoxin, but rather the passive consequence of epinephrine release.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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