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. 1960 Mar 31;111(4):441–451. doi: 10.1084/jem.111.4.441

IMMUNOLOGIC CROSS-REACTIONS AMONG MAMMALIAN ACUTE PHASE PROTEINS

Emil Gotschlich 1, Chandler A Stetson Jr 1
PMCID: PMC2137273  PMID: 13707424

Abstract

Crystalline rabbit Cx-reactive protein has been compared immunologically with the analogous crystalline C-reactive protein of man. Immunologic cross-reactivity has been demonstrated between the acute phase proteins of man, rabbit, and monkey. Double-diffusion reactions in agar and passive cutaneous anaphylaxis reactions in vivo both indicate that these acute phase proteins are antigenically closely similar but not identical. Guinea pigs with delayed hypersensitivity to C-reactive protein exhibit delayed skin reactions when tested with Cx-reactive protein and vice versa.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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