Abstract
Water movement in liver slices has been measured in the presence of varied oxygen supply and during the progress of gastrointestinal digestion. Maximum water intake occurs both with anoxia and with exposure to oxygen when animals have received no food during 20 to 24 hours. It diminishes almost immediately after the ingestion of food and is least after 8 to 10 hours when digestion is nearly complete. These changes coincide with the passage of amino acids from the gastrointestinal tract to the liver by way of the blood. Movement of water into the liver cells is favorable to the entrance of dissolved substances and when it is greatest with approaching anoxia the movement promotes the diffusion of oxygen into the cells.
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Selected References
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- DENTON A. E., ELVEHJEM C. A. Availability of amino acids in vivo. J Biol Chem. 1954 Jan;206(1):449–454. [PubMed] [Google Scholar]
- LONGENECKER J. B., HAUSE N. L. Relationship between plasma amino acids and composition of the ingested protein. Arch Biochem Biophys. 1959 Sep;84:46–59. doi: 10.1016/0003-9861(59)90552-1. [DOI] [PubMed] [Google Scholar]
- OPIE E. L. The relation of oxygen supply to water movement and to urea formation in surviving liver tissue. J Exp Med. 1961 Feb 1;113:339–352. doi: 10.1084/jem.113.2.339. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Opie E. L. THE RELATION OF UREA TO THE MOVEMENT OF WATER IN LIVER TISSUE. Proc Natl Acad Sci U S A. 1960 Apr;46(4):477–483. doi: 10.1073/pnas.46.4.477. [DOI] [PMC free article] [PubMed] [Google Scholar]