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. 1987 Sep;169(9):4384–4387. doi: 10.1128/jb.169.9.4384-4387.1987

Tunicamycin inhibition of epispore formation in Saccharomyces cerevisiae.

K G Weinstock, C E Ballou
PMCID: PMC213757  PMID: 3305484

Abstract

The ascopore wall of Saccharomyces cerevisiae was found to contain more protein, polymeric glucosamine, and beta-glucan than the vegetative cell wall, which was enriched in mannoprotein relative to ascospore walls. Tunicamycin inhibited sporulation, as judged by the absence of refractile ascospores visible by phase-contrast microscopy, but cells completed meiosis, as demonstrated by the presence of multinucleate asci. Such spores lacked the dense outer layer characteristic of normal spores. Thus, the tunicamycin effect was similar to that of glucosamine auxotrophy (W. L. Whelan and C. E. Ballou, J. Bacteriol. 124:1545-1557, 1975).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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