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. 1967 Feb 28;125(3):381–392. doi: 10.1084/jem.125.3.381

TYPE-SPECIFIC POLYSACCHARIDE ANTIGENS OF GROUP B STREPTOCOCCI

II. THE CHEMICAL BASIS FOR SEROLOGICAL SPECIFICITY OF THE TYPE II HCL ANTIGEN

Earl H Freimer 1
PMCID: PMC2138294  PMID: 6018238

Abstract

The type-specific antigen of Group B Type II streptococci has been prepared free of other known cell components. This antigen is a capsular polysaccharide containing D-galactose, D-glucose, N-acetyl-D-glucosamine, and a labile component which has not been chemically characterized. Extraction of Type II streptococci with cold TCA yielded this antigen which contained two serological determinants. A partial antigen with only one of the determinants was obtained by extraction with dilute HCl at 100°C. By means of the quantitative precipitin inhibition technique, a (β-D-galactopyranoside has been established as the determinant of the HCl-extracted polysaccharide. The second determinant, present solely in the TCA antigen, has not been identified.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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