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. 1966 Nov 30;124(6):1099–1106. doi: 10.1084/jem.124.6.1099

HIGH CONCENTRATION OF INJECTED TITANIUM DIOXIDE IN ABDOMINAL LYMPH NODES

Charles B Huggins 1, Jeffrey P Froehlich 1
PMCID: PMC2138331  PMID: 5925316

Abstract

In the rat the greatest accumulation, in any anatomical structure, of titanium dioxide following its intravenous injection was found in two small clusters of lymph nodes in upper abdomen behind the peritoneum. These are the lymph nodes of the liver. This extraordinary quantitative characteristic of the abdominal clusters is attributed to their topography which results in progressive filtration of particulate matter from hepatic lymph.

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Selected References

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  1. Pollard M., Kajima M., Teah B. A. Spontaneous leukemia in germfree AK mice. Proc Soc Exp Biol Med. 1965 Oct;120(1):72–75. doi: 10.3181/00379727-120-30446. [DOI] [PubMed] [Google Scholar]

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