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. 1969 Jun 1;129(6):1291–1306. doi: 10.1084/jem.129.6.1291

THE ENTRY OF GRANULE-ASSOCIATED PEROXIDASE INTO THE PHAGOCYTIC VACUOLES OF EOSINOPHILS

Ramzi S Cotran 1, Mortimer Litt 1
PMCID: PMC2138652  PMID: 4181945

Abstract

The ultrastructural localization of peroxidase was studied in guinea pig eosinophils which had phagocytized zymosan or Escherichia coli. After phagocytosis, the membrane of the granule was joined to the membrane of the phagocytic vacuole, and the enzyme, which is ordinarily restricted to the matrix of the granule, was seen in the vacuole surrounding the ingested particle.

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Selected References

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