Abstract
Two distinct particles have been recognized in the extracellular fluid of B. pertussis cultures. Both appeared to arise from the surface (cell wall) of the organism. One of these, a membranous particle, seemed to derive from long projections on the organism composed of the outer membrane of the cell wall. The second particle, a fine filament, was not readily comparable with any previously described bacterial structure. The two particles could be separated from each other by gradient centrifugation in CsCl. Lymphocytosis-promoting factor and histamine-sensitizing activity were only associated with fractions containing the fine filaments.
Full Text
The Full Text of this article is available as a PDF (1.3 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BLADEN H. A., MERGENHAGEN S. E. ULTRASTRUCTURE OF VEILLONELLA AND MORPHOLOGICAL CORRELATION OF AN OUTER MEMBRANE WITH PARTICLES ASSOCIATED WITH ENDOTOXIC ACTIVITY. J Bacteriol. 1964 Nov;88:1482–1492. doi: 10.1128/jb.88.5.1482-1492.1964. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bayer M. E., Anderson T. F. The surface structure of Escherichia coli. Proc Natl Acad Sci U S A. 1965 Dec;54(6):1592–1599. doi: 10.1073/pnas.54.6.1592. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Imaeda T., Kanetsuna F., Galindo B. Ultrastructure of cell walls of genus Mycobacterium. J Ultrastruct Res. 1968 Oct;25(1):46–63. doi: 10.1016/s0022-5320(68)80059-0. [DOI] [PubMed] [Google Scholar]
- Imaeda T., Kanetsuna F., Rieber M., Galindo B., Cesari I. M. Ultrastructural characteristics of mycobacterial growth. J Med Microbiol. 1969 Aug;2(3):181–186. doi: 10.1099/00222615-2-3-181. [DOI] [PubMed] [Google Scholar]
- Kuo T. T., Huang T. C., Chow T. Y. A filamentous bacteriophage from Xanthomonas oryzae. Virology. 1969 Nov;39(3):548–555. doi: 10.1016/0042-6822(69)90102-0. [DOI] [PubMed] [Google Scholar]
- Lane A. G. Appearance of mouse-lethal toxin in liquid cultures of Bordetella pertussis. Appl Microbiol. 1968 Sep;16(9):1400–1405. doi: 10.1128/am.16.9.1400-1405.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mason M. A. The spheroplasts of bordetella pertussis. Can J Microbiol. 1966 Jun;12(3):539–545. doi: 10.1139/m66-077. [DOI] [PubMed] [Google Scholar]
- Milleck J., Rockstroh T., Ocklitz H. W. Die Feinstruktur glycininduzierter Sphäroplasten im Vergleich zu der normaler Bakterienzellen von Bordetella pertussis. Zentralbl Bakteriol Orig. 1968;209(1):37–43. [PubMed] [Google Scholar]
- Morse S. I., Bray K. K. The occurrence and properties of leukocytosis and lymphocytosis-stimulating material in the supernatant fluids of Bordetella pertussis cultures. J Exp Med. 1969 Mar 1;129(3):523–550. doi: 10.1084/jem.129.3.523. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Munoz J., Bergman R. K. Histamine-sensitizing factors from microbial agents, with special reference to Bordetella pertussis. Bacteriol Rev. 1968 Jun;32(2):103–126. doi: 10.1128/br.32.2.103-126.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pieroni R. E., Broderick E. J., Levine L. The soluble protective antigen and the histamine-sensitizing factor of Bordetella pertussis. J Immunol. 1965 Oct;95(4):643–650. [PubMed] [Google Scholar]
- Work E., Knox K. W., Vesk M. The chemistry and electron microscopy of an extracellular lipopolysaccharide from Escherichia coli. Ann N Y Acad Sci. 1966 Jun 30;133(2):438–449. doi: 10.1111/j.1749-6632.1966.tb52382.x. [DOI] [PubMed] [Google Scholar]
- ZINDER N. D., VALENTINE R. C., ROGER M., STOECKENIUS W. F1, A ROD-SHAPED MALE-SPECIFIC BACTERIOPHAGE THAT CONTAINS DNA. Virology. 1963 Aug;20:638–640. doi: 10.1016/0042-6822(63)90290-3. [DOI] [PubMed] [Google Scholar]