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Chromosomal localization of COLQ by FISH. In situ hybridization was performed by using a digoxigenin-labeled human COLQ cDNA probe and normal metaphase cells from stimulated blood culture. (A) The digitized image of the COLQ probe signal is localized on both chromatids of 4′,6-diamidino-2-phenylindole-enhanced G-banded chromosome 3 from reverse imaging by the Vysis smartcapture system (Vysis, Downers Grove, IL). (B) COLQ is mapped to 3p25
