Abstract
TL- mice make TL antibody when immunized with spleen or bone marrow cells from TL+ donors, despite the fact that these cells do not express TL antigen. This has been shown to depend on maturation of TL- precursors, contained in the inoculum, into TL+ cells under influence of the recipient's thymus; the differentiated TL+ cells then evoke production of TL antibody.
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Selected References
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- Boyse E. A., Flaherty L., Stockert E., Old L. J. Histoincompatibility attributable to genes near H-2 that are not revealed by hemagglutination or cytotoxicity tests. Transplantation. 1972 Apr;13(4):431–432. doi: 10.1097/00007890-197204000-00013. [DOI] [PubMed] [Google Scholar]
- Schlesinger M., Boyse E. A., Old L. J. Thymus cells of radiation-chimeras: TL phenotype, sensitivity to guinea-pig serum, and origin from donor cells. Nature. 1965 Jun 12;206(989):1119–1121. doi: 10.1038/2061119a0. [DOI] [PubMed] [Google Scholar]