Abstract
A quantitative serological difference was found between strains Hz1 and M505 carrying mutant H-2 haplotypes ba and bd, respectively, and the original strain B6(H-2b). The finding suggests that the mutations occurred in the H-2Kb gene, and together with data on MLR and CML challenges the current concept of H-2 regions' involvement in immune reactions.
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Selected References
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- Bach F. H., Segall M., Zier K. S., Sondel P. M., Alter B. J., Bach M. L. Cell mediated immunity: separation of cells involved in recognitive and destructive phases. Science. 1973 Apr 27;180(4084):403–406. doi: 10.1126/science.180.4084.403. [DOI] [PubMed] [Google Scholar]
- Berke G., Amos D. B. Cytotoxic lymphocytes in the absence of detectable antibody. Nat New Biol. 1973 Apr 25;242(121):237–239. doi: 10.1038/newbio242237a0. [DOI] [PubMed] [Google Scholar]
- Hauptfeld V., Hauptfeld M., Klein J. Tissue distribution of I region-associated antigens in the mouse. J Immunol. 1974 Jul;113(1):181–188. [PubMed] [Google Scholar]
- Klein J., Klein D., Shreffler D. C. H-2 types of translocation stocks T(2;9)138Ca, T(9;13)-190Ca and an H-2 recombinant. Transplantation. 1970 Oct;10(4):309–320. doi: 10.1097/00007890-197010000-00006. [DOI] [PubMed] [Google Scholar]
- Riddle D. L., Carbon J. Frameshift suppression: a nucleotide addition in the anticodon of a glycine transfer RNA. Nat New Biol. 1973 Apr 25;242(121):230–234. doi: 10.1038/newbio242230a0. [DOI] [PubMed] [Google Scholar]
- Schendel D. J., Alter B. J., Bach F. H. The involvement of LD- and SD-region differences in MLC and CML: a three-cell experiment. Transplant Proc. 1973 Dec;5(4):1651–1655. [PubMed] [Google Scholar]
- Snell G. D., Démant P., Cherry M. Hemagglutination and cytotoxic studies of H-2. I. H-2.1 and related specificities in the EK crossover regions. Transplantation. 1971 Mar;11(3):210–237. doi: 10.1097/00007890-197103000-00002. [DOI] [PubMed] [Google Scholar]