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. 1974 Jul 1;140(1):290–295. doi: 10.1084/jem.140.1.290

CELL INTERACTIONS BETWEEN HISTOINCOMPATIBLE T AND B LYMPHOCYTES

VI. COOPERATIVE RESPONSES BETWEEN LYMPHOCYTES DERIVED FROM MOUSE DONOR STRAINS DIFFERING AT GENES IN THE S AND D REGIONS OF THEH-2 COMPLEX

David H Katz 1, Martin E Dorf 1, Baruj Benacerraf 1
PMCID: PMC2139692  PMID: 4545898

Abstract

In our initial studies on the question of histocompatibility requirements in T-B-cell interactions, we found that no cooperation occurred with mixtures of T and B cells from BALB/c (H-2d) and A/J (H-2a) donors, respectively (1). These particular strains are identical for genes in the S and D regions of the H-2 complex but possess major differences at the K-end. Many differences are known to exist in the I region as well. Thus, these early data indicated that gene identities only at the D-end are insufficient to permit optimal cooperative interactions to occur under these conditions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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