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. 1936 Jul 20;19(6):991–1007. doi: 10.1085/jgp.19.6.991

ISOLATION FROM BEEF PANCREAS OF CRYSTALLINE TRYPSINOGEN, TRYPSIN, A TRYPSIN INHIBITOR, AND AN INHIBITOR-TRYPSIN COMPOUND

M Kunitz 1, John H Northrop 1
PMCID: PMC2141477  PMID: 19872978

Abstract

Methods are described for the isolation and crystallization of trypsinogen, trypsin, a substance which inhibits trypsin, and an inhibitor-trypsin compound. Analyses and some of the properties of these compounds are given.

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Selected References

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  1. Kunitz M., Northrop J. H. AUTOCATALYTIC ACTIVATION OF TRYPSINOGEN IN THE PRESENCE OF CONCENTRATED AMMONIUM OR MAGNESIUM SULFATE. Science. 1934 Aug 24;80(2069):190–190. doi: 10.1126/science.80.2069.190. [DOI] [PubMed] [Google Scholar]
  2. Kunitz M., Northrop J. H. THE ISOLATION OF CRYSTALLINE TRYPSINOGEN AND ITS CONVERSION INTO CRYSTALLINE TRYPSIN. Science. 1934 Nov 30;80(2083):505–506. doi: 10.1126/science.80.2083.505. [DOI] [PubMed] [Google Scholar]

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