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. 1994 Apr;3(4):650–668. doi: 10.1002/pro.5560030413

Protein folding dynamics: the diffusion-collision model and experimental data.

M Karplus 1, D L Weaver 1
PMCID: PMC2142854  PMID: 8003983

Abstract

The diffusion-collision model of protein folding is assessed. A description is given of the qualitative aspects and quantitative results of the diffusion-collision model and their relation to available experimental data. We consider alternative mechanisms for folding and point out their relationship to the diffusion-collision model. We show that the diffusion-collision model is supported by a growing body of experimental and theoretical evidence, and we outline future directions for developing the model and its applications.

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Selected References

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