Abstract
Inhibition of DNA synthesis prevented the recovery of cell division in filaments of D-3R [ftsA3(Ts) recA56] returned to the permissive temperature. The FtsA protein may be a signal involved in the "TER" pathway, a series of events that coordinate cell division with DNA replication, that is independent of the SOS pathway.
Full text
PDF![950](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29bf/214349/506ae48aec95/jbacter00216-0466.png)
![951](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29bf/214349/98f17f89cd0a/jbacter00216-0467.png)
![952](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29bf/214349/4a606a9f235b/jbacter00216-0468.png)
![953](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29bf/214349/908b4bbdbb0e/jbacter00216-0469.png)
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Clark D. J. Regulation of deoxyribonucleic acid replication and cell division in Escherichia coli B-r. J Bacteriol. 1968 Oct;96(4):1214–1224. doi: 10.1128/jb.96.4.1214-1224.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Csonka L. N., Clark A. J. Construction of an Hfr strain useful for transferring recA mutations between Escherichia coli strains. J Bacteriol. 1980 Jul;143(1):529–530. doi: 10.1128/jb.143.1.529-530.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Donachie W. D., Begg K. J., Lutkenhaus J. F., Salmond G. P., Martinez-Salas E., Vincente M. Role of the ftsA gene product in control of Escherichia coli cell division. J Bacteriol. 1979 Nov;140(2):388–394. doi: 10.1128/jb.140.2.388-394.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Helmstetter C. E., Pierucci O. Cell division during inhibition of deoxyribonucleic acid synthesis in Escherichia coli. J Bacteriol. 1968 May;95(5):1627–1633. doi: 10.1128/jb.95.5.1627-1633.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Howe W. E., Mount D. W. Analysis of cell division in single clones of the Escherichia coli K-12 lexA mutant. J Bacteriol. 1978 Mar;133(3):1278–1281. doi: 10.1128/jb.133.3.1278-1281.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Howe W. E., Mount D. W. Production of cells without deoxyribonucleic acid during thymidine starvation of lexA- cultures of Escherichia coli K-12. J Bacteriol. 1975 Dec;124(3):1113–1121. doi: 10.1128/jb.124.3.1113-1121.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Huisman O., D'Ari R. An inducible DNA replication-cell division coupling mechanism in E. coli. Nature. 1981 Apr 30;290(5809):797–799. doi: 10.1038/290797a0. [DOI] [PubMed] [Google Scholar]
- Huisman O., D'Ari R., George J. Inducible sfi dependent division inhibition in Escherichia coli. Mol Gen Genet. 1980;177(4):629–636. doi: 10.1007/BF00272673. [DOI] [PubMed] [Google Scholar]
- Huisman O., D'Ari R., Gottesman S. Cell-division control in Escherichia coli: specific induction of the SOS function SfiA protein is sufficient to block septation. Proc Natl Acad Sci U S A. 1984 Jul;81(14):4490–4494. doi: 10.1073/pnas.81.14.4490. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Inouye M. Pleiotropic effect of the rec A gene of Escherichia coli: uncoupling of cell division from deoxyribonucleic acid replication. J Bacteriol. 1971 May;106(2):539–542. doi: 10.1128/jb.106.2.539-542.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jones C. A., Holland I. B. Inactivation of essential division genes, ftsA, ftsZ, suppresses mutations at sfiB, a locus mediating division inhibition during the SOS response in E. coli. EMBO J. 1984 May;3(5):1181–1186. doi: 10.1002/j.1460-2075.1984.tb01948.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jones N. C., Donachie W. D. Chromosome replication, transcription and control of cell division in Escherichia coli. Nat New Biol. 1973 May 23;243(125):100–103. [PubMed] [Google Scholar]
- Little J. W., Mount D. W. The SOS regulatory system of Escherichia coli. Cell. 1982 May;29(1):11–22. doi: 10.1016/0092-8674(82)90085-x. [DOI] [PubMed] [Google Scholar]
- Lutkenhaus J. F. Coupling of DNA replication and cell division: sulB is an allele of ftsZ. J Bacteriol. 1983 Jun;154(3):1339–1346. doi: 10.1128/jb.154.3.1339-1346.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lutkenhaus J. F., Donachie W. D. Identification of the ftsA gene product. J Bacteriol. 1979 Mar;137(3):1088–1094. doi: 10.1128/jb.137.3.1088-1094.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lutkenhaus J. F., Wolf-Watz H., Donachie W. D. Organization of genes in the ftsA-envA region of the Escherichia coli genetic map and identification of a new fts locus (ftsZ). J Bacteriol. 1980 May;142(2):615–620. doi: 10.1128/jb.142.2.615-620.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lutkenhaus J. F., Wu H. C. Determination of transcriptional units and gene products from the ftsA region of Escherichia coli. J Bacteriol. 1980 Sep;143(3):1281–1288. doi: 10.1128/jb.143.3.1281-1288.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Oostra B. A., van Vliet A. J., Ab G., Gruber M. Enhancement of ribosomal ribonucleic acid synthesis by deoxyribonucleic acid gyrase activity in Escherichia coli. J Bacteriol. 1981 Dec;148(3):782–787. doi: 10.1128/jb.148.3.782-787.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ostrowski J., Hulanicka D. Effect of DNA gyrase inhibitors on gene expression of the cysteine regulon. Mol Gen Genet. 1981;181(3):363–366. doi: 10.1007/BF00425612. [DOI] [PubMed] [Google Scholar]
- Tormo A., Fernández-Cabrera C., Vicente M. The ftsA gene product: a possible connection between DNA replication and septation in Escherichia coli. J Gen Microbiol. 1985 Feb;131(2):239–244. doi: 10.1099/00221287-131-2-239. [DOI] [PubMed] [Google Scholar]
- Tormo A., Martínez-Salas E., Vicente M. Involvement of the ftsA gene product in late stages of the Escherichia coli cell cycle. J Bacteriol. 1980 Feb;141(2):806–813. doi: 10.1128/jb.141.2.806-813.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tormo A., Vicente M. The ftsA gene product participates in formation of the Escherichia coli septum structure. J Bacteriol. 1984 Mar;157(3):779–784. doi: 10.1128/jb.157.3.779-784.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Witkin E. M. Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. Bacteriol Rev. 1976 Dec;40(4):869–907. doi: 10.1128/br.40.4.869-907.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- de Massy B., Patte J., Louarn J. M., Bouché J. P. oriX: a new replication origin in E. coli. Cell. 1984 Jan;36(1):221–227. doi: 10.1016/0092-8674(84)90092-8. [DOI] [PubMed] [Google Scholar]