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. 1986 Jan;165(1):193–197. doi: 10.1128/jb.165.1.193-197.1986

Isolation and characterization of lon mutants in Salmonella typhimurium.

D Downs, L Waxman, A L Goldberg, J Roth
PMCID: PMC214388  PMID: 3001022

Abstract

In this paper we report the isolation and characterization of lon mutants in Salmonella typhimurium. The mutants were isolated by using positive selection by chlorpromazine resistance. The physiological and biochemical properties of the lon mutants in S. typhimurium are very similar to those of Escherichia coli lon mutants. Mutants altered at this locus contain little or no activity of the ATP-dependent protease La and show a number of pleiotropic phenotypes, including increased production of capsular polysaccharides, increased sensitivity to UV light and other DNA-damaging agents, and a decreased ability to degrade abnormal proteins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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