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. 1992 Sep;38:2123-2124, 2127-2130, 2133-2134, 2174.

Carbon Monoxide Toxicity

The difficulty in diagnosing this leading cause of poisoning

Michael J Aniol
PMCID: PMC2145489  PMID: 21221282

Abstract

Of all fatal poisonings in the United States, an estimated half are due to carbon monoxide. The number of non-lethal poisonings due to carbon monoxide is difficult to estimate because signs and symptoms of carbon monoxide poisoning cover a wide spectrum and mimic other disorders. Misdiagnosis is serious, as the patient often returns to the contaminated environment. Those not receiving proper treatment are at significant risk, as high as 10% to 12%, of developing late neurological sequelae. The diagnosis of carbon monoxide poisoning depends upon precise history taking, careful physical examination, and a high index of suspicion.

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Selected References

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  1. Anderson E. W., Andelman R. J., Strauch J. M., Fortuin N. J., Knelson J. H. Effect of low-level carbon monoxide exposure on onset and duration of angina pectoris. A study in ten patients with ischemic heart disease. Ann Intern Med. 1973 Jul;79(1):46–50. doi: 10.7326/0003-4819-79-1-46. [DOI] [PubMed] [Google Scholar]
  2. Coburn R. F. The carbon monoxide body stores. Ann N Y Acad Sci. 1970 Oct 5;174(1):11–22. doi: 10.1111/j.1749-6632.1970.tb49768.x. [DOI] [PubMed] [Google Scholar]
  3. Dempsey L. C., O'Donnell J. J., Hoff J. T. Carbon monoxide retinopathy. Am J Ophthalmol. 1976 Nov;82(5):692–693. doi: 10.1016/0002-9394(76)90003-9. [DOI] [PubMed] [Google Scholar]
  4. Ginsberg M. D., Myers R. E., McDonagh B. F. Experimental carbon monoxide encephalopathy in the primate. II. Clinical aspects, neuropathology, and physiologic correlation. Arch Neurol. 1974 Mar;30(3):209–216. doi: 10.1001/archneur.1974.00490330017003. [DOI] [PubMed] [Google Scholar]
  5. González A., Gómez-Arnau J., Pensado A. Carboxyhemoglobin and pulse oximetry. Anesthesiology. 1990 Sep;73(3):573–573. doi: 10.1097/00000542-199009000-00038. [DOI] [PubMed] [Google Scholar]
  6. Johnson C. J., Moran J. C., Paine S. C., Anderson H. W., Breysse P. A. Abatement of toxic levels of carbon monoxide in Seattle ice-skating rinks. Am J Public Health. 1975 Oct;65(10):1087–1090. doi: 10.2105/ajph.65.10.1087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Raybourn M. S., Cork C., Schimmerling W., Tobias C. A. An in vitro electrophysiological assessment of the direct cellular toxicity of carbon monoxide. Toxicol Appl Pharmacol. 1978 Dec;46(3):769–779. doi: 10.1016/0041-008x(78)90321-6. [DOI] [PubMed] [Google Scholar]
  8. Sawada Y., Sakamoto T., Nishide K., Sadamitsu D., Fusamoto H., Yoshioka T., Sugimoto T., Onishi S. Correlation of pathological findings with computed tomographic findings after acute carbon monoxide poisoning. N Engl J Med. 1983 May 26;308(21):1296–1296. [PubMed] [Google Scholar]
  9. Stewart R. D., Hake C. L. Paint-remover hazard. JAMA. 1976 Jan 26;235(4):398–401. [PubMed] [Google Scholar]

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