Skip to main content
The Journal of General Physiology logoLink to The Journal of General Physiology
. 1950 Nov 20;34(2):161–166. doi: 10.1085/jgp.34.2.161

THE INFLUENCE OF INSULIN ON THE RATE OF GLUCOSE OXIDATION BY PASTEURELLA PESTIS

H B Levine 1
PMCID: PMC2147249  PMID: 14824488

Abstract

The rate of oxidation of glucose by freshly harvested resting cells of P. pestis strain A-1122 was accelerated by 20 to 41 per cent in the presence of insulin. The stimulatory action was not noted when cell-free enzyme preparations were employed and was less marked after storage of cells for 3 days. Although insulin was not oxidized by the organism, the amount of oxygen consumed during the dissimilation of a unit weight of glucose was increased in the presence of the hormone.

Full Text

The Full Text of this article is available as a PDF (345.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Broh-Kahn R. H., Mirsky I. A. Hexokinase Activity and Diabetes Mellitus. Science. 1947 Aug 15;106(2746):148–149. doi: 10.1126/science.106.2746.148. [DOI] [PubMed] [Google Scholar]
  2. LEVINE R., GOLDSTEIN M. The action of insulin on the distribution of galactose in eviscerated nephrectomized dogs. J Biol Chem. 1949 Jun;179(2):985–985. [PubMed] [Google Scholar]
  3. STADIE W. C., HAUGAARD N. The hexokinase reaction in tissue extracts from normal and diabetic rats. J Biol Chem. 1949 Jan;177(1):311–324. [PubMed] [Google Scholar]

Articles from The Journal of General Physiology are provided here courtesy of The Rockefeller University Press

RESOURCES