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. 1951 Sep 20;35(1):17–22. doi: 10.1085/jgp.35.1.17

THE ACTION OF SOME HEMOLYSIS ACCELERATORS UPON LIPID AND PROTEIN MONOLAYERS

Helen L Chen 1, H B Collier 1
PMCID: PMC2147296  PMID: 14873917

Abstract

The effect of three accelerators of hemolysis—acetylphenylhydrazine, 9-aminoacridine, and phenothiazone—upon protein and lipid monolayers has been examined. These compounds, in low concentration, cause marked expansion of monolayers of plasma albumin, but have no apparent effect upon cholesterol films. It is suggested that these accelerators may affect the protein component of the erythrocyte membrane, thus enhancing the action of hemolytic agents.

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Selected References

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  1. Schulman J. H., Hughes A. H. Monolayers of proteolytic enzymes and proteins: Mixed unimolecular films. Biochem J. 1935 May;29(5):1243–1252. doi: 10.1042/bj0291243. [DOI] [PMC free article] [PubMed] [Google Scholar]

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