Abstract
Preparations from the parotid gland venom of the toad Bufo marinus have been analyzed by paper chromatography for the presence of adrenalin precursors. In addition to adrenalin itself, hydroxytyramine was identified and a second compound which appeared to be an adrenalin ester—perhaps lactyl-adrenalin. Two other compounds which appeared on the chromatogram could not be identified. Neither noradrenalin nor another possible precursor, epinine, appeared to be present.
Full Text
The Full Text of this article is available as a PDF (336.8 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Goldenberg M., Faber M., Alston E. J., Chargaff E. C. Evidence for the Occurrence of Nor-Epinephrine in the Adrenal Medulla. Science. 1949 May 27;109(2839):534–535. doi: 10.1126/science.109.2839.534. [DOI] [PubMed] [Google Scholar]
- LEE H. M., CHEN K. K. The occurrence of nor-epinephrine in the Chinese toad venom. J Pharmacol Exp Ther. 1951 Aug;102(4):286–290. [PubMed] [Google Scholar]
- Partridge S. M. Filter-paper partition chromatography of sugars: 1. General description and application to the qualitative analysis of sugars in apple juice, egg white and foetal blood of sheep. with a note by R. G. Westall. Biochem J. 1948;42(2):238–250. doi: 10.1042/bj0420238. [DOI] [PMC free article] [PubMed] [Google Scholar]
- VON EULER U. S. Preparation, purification and evaluation of noradrenaline and adrenaline in organ extracts. Arch Int Pharmacodyn Ther. 1948 Nov 1;77(4):477–485. [PubMed] [Google Scholar]
