Abstract
The treatment in this paper of available quantitative data on the response of taste receptors to sodium salt stimulation clearly indicates that the ions of the chemical stimulus are loosely bound to some substance of the taste receptor. This can be thought of as an initial reaction which ultimately leads to stimulation of the receptor and an eventual depolarization of the associated sensory neuron. The speed of the total reaction suggests that the receptor substance is located on or near the surface of the receptor. The recently proposed (7) enzymatic reactions for chemoreceptors do not appear plausible for sodium salt stimulation of the taste receptors of the rat.
Full Text
The Full Text of this article is available as a PDF (428.0 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BARADI A. F., BOURNE G. H. Localization of gustatory and olfactory enzymes in the rabbit, and the problems of taste and smell. Nature. 1951 Dec 8;168(4284):977–979. doi: 10.1038/168977a0. [DOI] [PubMed] [Google Scholar]
- LANSING A. I., ROSENTHAL T. B. The relation between ribonucleic acid and ionic transport across the cell surface. J Cell Physiol. 1952 Oct;40(2):337–345. doi: 10.1002/jcp.1030400212. [DOI] [PubMed] [Google Scholar]
- SHACK J., JENKINS R. J., THOMPSETT J. M. The binding of sodium chloride and calf thymus desoxypentose nucleic acid. J Biol Chem. 1952 Sep;198(1):85–92. [PubMed] [Google Scholar]