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. 1984 Nov;160(2):493–498. doi: 10.1128/jb.160.2.493-498.1984

Nitrogen regulation of amino acid utilization by Neurospora crassa.

R M DeBusk, S Ogilvie
PMCID: PMC214760  PMID: 6238945

Abstract

The production of an extracellular deaminase activity involved with the utilization of amino acids as sole sources of nitrogen is under the control of the nit-2 locus of Neurospora crassa. This locus is the sole major nitrogen regulatory locus described for N. crassa and is believed to encode a positive effector required for induction of activities involved with the utilization of alternate nitrogen sources. Production of deaminase activity requires the lifting of nitrogen metabolite repression, the presence of a functional nit-2 gene product, and specific induction by amino acids. Additional parameters of enzyme production are described.

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Selected References

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