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. 1984 Nov;160(2):812–814. doi: 10.1128/jb.160.2.812-814.1984

Inhibitory effect of Li+ on cell growth and pyruvate kinase activity of Escherichia coli.

K Umeda, S Shiota, M Futai, T Tsuchiya
PMCID: PMC214814  PMID: 6389501

Abstract

Li+ inhibited growth of Escherichia coli when glucose, galactose, fructose, or glycerol was added as the sole source of carbon. Growth inhibition was not observed when lactate or a mixture of amino acids was used as the carbon source. A mutant possessing elevated activity of Li+ extrusion was not inhibited by Li+. These results suggested that intracellular Li+ inhibited the glycolytic pathway, most likely triose metabolism, without affecting gluconeogenesis. We also found that pyruvate kinase I was inhibited by Li+.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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