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. 1991 Mar-Apr;38(2):69–71.

Epidural buprenorphine or morphine for the relief of head and neck cancer pain.

Y Hashimoto 1, T Utsumi 1, H Tanioka 1, B M Rigor 1
PMCID: PMC2148689  PMID: 1811431

Abstract

We present three cases in which epidural buprenorphine or morphine was used for intractable cancer pain of the head and neck. Excellent pain relief and minimal side effects offered by epidural opioids were of significant benefit. The use of epidural opioids prior to the administration of high doses of oral morphine may be the treatment of choice for pain from malignancy of the head and neck, especially when there is tumor extension or distant metastasis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bromage P. R., Camporesi E. M., Durant P. A., Nielsen C. H. Rostral spread of epidural morphine. Anesthesiology. 1982 Jun;56(6):431–436. doi: 10.1097/00000542-198206000-00004. [DOI] [PubMed] [Google Scholar]
  2. Busch E. H., Stedman P. M. Epidural morphine for postoperative pain on medical-surgical wards--a clinical review. Anesthesiology. 1987 Jul;67(1):101–104. doi: 10.1097/00000542-198707000-00019. [DOI] [PubMed] [Google Scholar]
  3. Cobb C. A., 3rd, French B. N., Smith K. A. Intrathecal morphine for pelvic and sacral pain caused by cancer. Surg Neurol. 1984 Jul;22(1):63–68. doi: 10.1016/0090-3019(84)90231-3. [DOI] [PubMed] [Google Scholar]
  4. Fields H. L., Emson P. C., Leigh B. K., Gilbert R. F., Iversen L. L. Multiple opiate receptor sites on primary afferent fibres. Nature. 1980 Mar 27;284(5754):351–353. doi: 10.1038/284351a0. [DOI] [PubMed] [Google Scholar]
  5. Gourlay G. K., Cherry D. A., Cousins M. J. Cephalad migration of morphine in CSF following lumbar epidural administration in patients with cancer pain. Pain. 1985 Dec;23(4):317–326. doi: 10.1016/0304-3959(85)90001-6. [DOI] [PubMed] [Google Scholar]
  6. Kitahata L. M., Kosaka Y., Taub A., Bonikos K., Hoffert M. Lamina-specific suppression of dorsal-horn unit activity by morphine sulfate. Anesthesiology. 1974 Jul;41(1):39–48. doi: 10.1097/00000542-197407000-00008. [DOI] [PubMed] [Google Scholar]
  7. Magora F., Olshwang D., Eimerl D., Shorr J., Katzenelson R., Cotev S., Davidson J. T. Observations on extradural morphine analgesia in various pain conditions. Br J Anaesth. 1980 Mar;52(3):247–252. doi: 10.1093/bja/52.3.247. [DOI] [PubMed] [Google Scholar]
  8. Sullivan S. P., Cherry D. A. Pain from an invasive facial tumor relieved by lumbar epidural morphine. Anesth Analg. 1987 Aug;66(8):777–779. [PubMed] [Google Scholar]
  9. Waldman S. D., Feldstein G. S., Allen M. L., Landers M., Turnage G. Cervical epidural implantable narcotic delivery systems in the management of upper body cancer pain. Anesth Analg. 1987 Aug;66(8):780–782. [PubMed] [Google Scholar]
  10. Wang J. K., Nauss L. A., Thomas J. E. Pain relief by intrathecally applied morphine in man. Anesthesiology. 1979 Feb;50(2):149–151. doi: 10.1097/00000542-197902000-00013. [DOI] [PubMed] [Google Scholar]
  11. Yablonski-Peretz T., Klin B., Beilin Y., Warner E., Baron S., Olshwang D., Catane R. Continuous epidural narcotic analgesia for intractable pain due to malignancy. J Surg Oncol. 1985 May;29(1):8–10. doi: 10.1002/jso.2930290104. [DOI] [PubMed] [Google Scholar]
  12. Yaksh T. L., Rudy T. A. Analgesia mediated by a direct spinal action of narcotics. Science. 1976 Jun 25;192(4246):1357–1358. doi: 10.1126/science.1273597. [DOI] [PubMed] [Google Scholar]

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