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Anesthesia Progress logoLink to Anesthesia Progress
. 1994;41(1):6–10.

Effective postoperative pain prevention through administration of bupivacaine and diclofenac.

T Hyrkäs 1, P Ylipaavalniemi 1, V J Oikarinen 1, I Paakkari 1
PMCID: PMC2148714  PMID: 8629744

Abstract

The efficacies of bupivacaine and lidocaine together with a preoperatively administered single-dose oral combination of normal- and sustained-release preparations of diclofenac in preventing postoperative pain after third molar removal were compared in a double-blind crossover study. Bilaterally impacted lower third molars were removed in two sessions. Each patient was given one type of local anesthetic on one session and the other in the second. Pain was recorded using a visual analog scale. When the diclofenac combination (150 mg) was given before the operation, postoperative analgesia was better with bupivacaine plus diclofenac than with lidocaine plus diclofenac. Twenty-five out of 40 patients preferred bupivacaine to lidocaine for local anesthesia. It is possible to achieve effective postoperative pain prevention by combining bupivacaine and preoperative normal- and sustained-release preparations of diclofenac.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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