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. 1999 Summer;46(3):97–99.

Clinical effectiveness of lidocaine and benzocaine for topical anesthesia.

A L Rosa 1, C E Sverzut 1, S P Xavier 1, M A Lavrador 1
PMCID: PMC2148990  PMID: 11692349

Abstract

The effectiveness of lidocaine and benzocaine in reducing pain produced by needle insertion into the palate was evaluated in a double-blind and placebo-controlled study using a more suitable method. Twenty subjects, 10 men and 10 women, submitted to 4 sessions in which they were randomly treated with 5% lidocaine, a placebo that tasted like lidocaine, 20% benzocaine, and a placebo that tasted like benzocaine. At each session, a 27-gauge needle was inserted into the palate twice, once before (baseline) and once after drug application for 1 minute. Immediately after each insertion, subjects indicated on a visual analog scale the pain intensity perceived. Lidocaine and benzocaine were equally efficient, and both were better than placebo in reducing pain caused by insertion of needles into the palate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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