Abstract
Immune mechanisms appear to contribute to the good response of choriocarcinoma to chemotherapy. Immunosuppression induced by an advanced state of the disease or by therapy is disadvantageous to the chemotherapeutic response. The antigens concerned in the immune responses have not been identified but present evidence points away from known allospecific antigens as a major contributor to the responsiveness of this tumour.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bagshawe K. D., Rawlins G., Pike M. C., Lawler S. D. ABO blood-groups in trophoblastic neoplasia. Lancet. 1971 Mar 20;1(7699):553–556. doi: 10.1016/s0140-6736(71)91159-7. [DOI] [PubMed] [Google Scholar]
- Bagshawe K. D., Wilson H., Dublon P., Smith A., Baldwin M., Kardana A. Follow-up after hydatidiform mole: studies using radioimmunoassay for urinary human chorionic gonadotrophin (HCG). J Obstet Gynaecol Br Commonw. 1973 May;80(5):461–468. doi: 10.1111/j.1471-0528.1973.tb15962.x. [DOI] [PubMed] [Google Scholar]
- Elston C. W., Bagshawe K. D. Cellular reaction in trophoblastic tumours. Br J Cancer. 1973 Sep;28(3):245–256. doi: 10.1038/bjc.1973.144. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elston C. W. Cellular reaction to choriocarcinoma. J Pathol. 1969 Feb;97(2):261–268. doi: 10.1002/path.1710970211. [DOI] [PubMed] [Google Scholar]
- Klouda P. T., Lawler S. D., Bagshawe K. D. HL-A matings in trophoblastic neoplasia. Tissue Antigens. 1972;2(3):280–284. doi: 10.1111/j.1399-0039.1972.tb00146.x. [DOI] [PubMed] [Google Scholar]
- Lawler S. D., Klouda P. T., Bagshawe K. D. The HL-A system in trophoblastic neoplasia. Lancet. 1971 Oct 16;2(7729):834–837. doi: 10.1016/s0140-6736(71)90217-0. [DOI] [PubMed] [Google Scholar]
- Ratnam S. S., Teoh E. S., Dawood M. Y. Methotrexate for prophylaxis of choriocarcinoma. Am J Obstet Gynecol. 1971 Dec 15;111(8):1021–1027. doi: 10.1016/0002-9378(71)90097-4. [DOI] [PubMed] [Google Scholar]
