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. 1985 Feb;161(2):758–763. doi: 10.1128/jb.161.2.758-763.1985

Separate resistances to arsenate and arsenite (antimonate) encoded by the arsenical resistance operon of R factor R773.

C M Chen, H L Mobley, B P Rosen
PMCID: PMC214947  PMID: 3881408

Abstract

The arsenical resistance operon of R factor R773 was analyzed by subcloning and insertional inactivation. The operon was found to have two functional regions, the promoter-proximal region encoding resistance to arsenite and antimonate and the promoter-distal region encoding arsenate resistance. A unique 1.6-kilobase fragment was shown to be sufficient to encode arsenate resistance and produce arsenate extrusion from intact cells.

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Selected References

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