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The British Journal of Cancer. Supplement logoLink to The British Journal of Cancer. Supplement
. 1990 Jul;10:30–33.

99mTc radioimmunoscintigraphy of colorectal cancer.

M Granowska 1, S J Mather 1, K E Britton 1, S Bentley 1, P Richman 1, R K Phillips 1, J M Northover 1
PMCID: PMC2149513  PMID: 2166551

Abstract

The monoclonal antibody PR1A3 against a normal colonic columnar cell surface antigen has been labelled with 99mTc and used for imaging colorectal cancer. High uptake in undifferentiated cancer is seen. The tumour to mucosa ratio was up to 63:1 and the percentage of the injected activity in the tumour up to 1.7 X 10(-2%)g-1. As 99mTc is continuously available in a Nuclear Medicine Department, on receipt of a request the study may be completed within 24 h enabling radioimmunoscintigraphy to be used routinely in the management of patients with colorectal cancer.

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Selected References

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