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. 1994 Sep;23:S34–S36.

Viruses and Langerhans cell histiocytosis: is there a link?

K McClain 1, R A Weiss 1
PMCID: PMC2149698  PMID: 8075003

Abstract

As a rare, sporadic disease Langerhans cell histiocytosis (LCH) presents a difficult problem in defining a likely etiology. Epidemiological data would not a priori lead one to choose a viral etiology. However, there are rare tumours which occur as sequelae of common infections from Epstein-Barr virus or human papilloma viruses. Likewise some viruses can cause cells to elaborate cytokines which could ultimately stimulate Langerhans cell growth. There is only a small amount of experimental data testing the hypothesis that viruses might be associated with LCH. The theoretical constructs surrounding this question and new data refuting the association are summarised.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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