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. 1985 Mar;161(3):1029–1033. doi: 10.1128/jb.161.3.1029-1033.1985

Pyrimidine deoxyribonucleotide metabolism in Acholeplasma laidlawii B-PG9.

M V Williams, J D Pollack
PMCID: PMC215002  PMID: 3972768

Abstract

Extracts of Acholeplasma laidlawii B-PG9 were examined for the enzymes associated with the interconversion of the pyrimidine deoxyribonucleotides and the biosynthesis of thymidine nucleotides. A. laidlawii B-PG9 possessed deaminases for deoxycytidine and dCMP, pyrophosphatases for dUTP, phosphorylases for thymidine and uridine, and a membrane-associated pyrimidine deoxyribonucleoside monophosphate phosphatase activity. The role these enzyme activities have in the generation of deoxyribose-1-phosphate during growth may explain the ability of A. laidlawii B-PG9 to utilize either thymine or thymidine for biosynthesis.

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Selected References

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