Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1985 Mar;161(3):1236–1237. doi: 10.1128/jb.161.3.1236-1237.1985

Type III 5-methylcytosine modification of DNA in Neisseria gonorrhoeae.

C Korch, P Hagblom, S Normark
PMCID: PMC215036  PMID: 3918988

Abstract

We present here the first report of a type III methyltransferase that modifies a cytosine. Neisseria gonorrhoeae 82409/55 (pJD1) modifies the first cytosine on only one strand from the 5' end of the nonpalindromic sequence: (Formula; see text). We have called this modifying activity M X NgoVIII.

Full text

PDF
1236

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Korch C., Hagblom P., Normark S. Sequence-specific DNA modification in Neisseria gonorrhoeae. J Bacteriol. 1983 Sep;155(3):1324–1332. doi: 10.1128/jb.155.3.1324-1332.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Maxam A. M., Gilbert W. Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 1980;65(1):499–560. doi: 10.1016/s0076-6879(80)65059-9. [DOI] [PubMed] [Google Scholar]
  3. Norlander L., Davies J. K., Hagblom P., Normark S. Deoxyribonucleic acid modifications and restriction endonuclease production in Neisseria gonorrhoeae. J Bacteriol. 1981 Feb;145(2):788–795. doi: 10.1128/jb.145.2.788-795.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Ohmori H., Tomizawa J. I., Maxam A. M. Detection of 5-methylcytosine in DNA sequences. Nucleic Acids Res. 1978 May;5(5):1479–1485. doi: 10.1093/nar/5.5.1479. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Roberts R. J. Restriction and modification enzymes and their recognition sequences. Nucleic Acids Res. 1983 Jan 11;11(1):r135–r167. [PMC free article] [PubMed] [Google Scholar]
  6. Yuan R. Structure and mechanism of multifunctional restriction endonucleases. Annu Rev Biochem. 1981;50:285–319. doi: 10.1146/annurev.bi.50.070181.001441. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES