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. 1984 Feb;157(2):632–636. doi: 10.1128/jb.157.2.632-636.1984

Pyocin R1 inhibits active transport in Pseudomonas aeruginosa and depolarizes membrane potential.

Y Uratani, T Hoshino
PMCID: PMC215293  PMID: 6420392

Abstract

Pyocin R1, a bacteriocin of Pseudomonas aeruginosa, inhibited active transport of proline in the presence of high concentrations of malate and magnesium salt. Pyocin R1 did not affect the respiration of sensitive cells nor induce cell lysis, but it caused a decrease in the intracellular ATP level. In addition, a passive inflow of [14C]thiocyanate anion, a probe of membrane potential, was induced by pyocin R1, showing a depolarization of the cytoplasmic membrane. It is considered that membrane depolarization is a primary action of pyocin R1.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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