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. 1984 Apr;158(1):337–339. doi: 10.1128/jb.158.1.337-339.1984

Activation of trehalase by membrane-depolarizing agents in yeast vegetative cells and ascospores.

J M Thevelein
PMCID: PMC215419  PMID: 6370962

Abstract

The membrane-depolarizing agents 2,4-dinitrophenol, carbonylcyanide m-chlorophenylhydrazone, and nystatin are known to cause a rapid increase in the cyclic AMP level in fungal cells. Addition of these proton ionophores to yeast stationary-phase cells or ascospores causes an immediate 10-fold increase in trehalase activity. This observation is in agreement with a role for cyclic AMP-induced phosphorylation in the activation process of trehalase. It also provides an explanation for previous results on the induction of trehalose breakdown by 2,4-dinitrophenol in resting yeast cells.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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