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. 1984 Apr;158(1):347–350. doi: 10.1128/jb.158.1.347-350.1984

Metabolism of dihydrouracil in Rhodosporidium toruloides.

C H Davis, M D Putnam, W M Thwaites
PMCID: PMC215422  PMID: 6425266

Abstract

Previous studies, including those done with a similar species, have indicated that dihydrouracil is formed by the breakdown of uracil and is degraded into N-carbamyl-beta-alanine. (Fink et al., J. Biol. Chem. 201:349-355, 1953; S. R. Vilks and M. Y. Vitols, Mikrobiologiya 42:567-583, 1973; O. A. Milstein and M. L. Bekker, J. Bacteriol. 127:1-6, 1976). In the present work the conversion of dihydrouracil to uracil is studied in Rhodosporidium toruloides, and the growth characteristics of mutants that have lost the ability to use dihydrouracil as a source of nitrogen are examined. It is concluded that dihydrouracil must be converted to uracil before catabolism of the pyrimidine ring can take place.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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