Abstract
Systemic lupus erythematosus (SLE) is a chronic inflammatory disease of the connective tissue, affecting many organs of the body. The cause of SLE remains unknown, but the results of recent immunologic research have enlighted the characteristics of this disease and have contributed to improve the prognosis over the years. The renal and central nervous system involvement, as well as infection, remain high in the list of mortality causes. The usual treatment includes acetylsalicylic acid (ASA), antimalarials and corticosteroids. Main factors known to induce SLE are: sun exposures, pregnancy, therapeutic abortion, infection and several drugs.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Karsh J., Kimberly R. P., Stahl N. I., Plotz P. H., Decker J. L. Comparative effects of aspirin and ibuprofen in the management of systemic lupus erythematosus. Arthritis Rheum. 1980 Dec;23(12):1401–1404. doi: 10.1002/art.1780231215. [DOI] [PubMed] [Google Scholar]
- Kimberly R. P., Lockshin M. D., Sherman R. L., McDougal J. S., Inman R. D., Christian C. L. High-dose intravenous methylprednisolone pulse therapy in systemic lupus erythematosus. Am J Med. 1981 Apr;70(4):817–824. doi: 10.1016/0002-9343(81)90538-6. [DOI] [PubMed] [Google Scholar]
- Pepys M. B., Lanham J. G., De Beer F. C. C-reactive protein in SLE. Clin Rheum Dis. 1982 Apr;8(1):91–103. [PubMed] [Google Scholar]
- Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F., Schaller J. G., Talal N., Winchester R. J. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 Nov;25(11):1271–1277. doi: 10.1002/art.1780251101. [DOI] [PubMed] [Google Scholar]
- Travers R. L., Hughes G. R. Salicylate hepatotoxicity in systemic lupus erythematosus: a common occurrence? Br Med J. 1978 Dec 2;2(6151):1532–1533. doi: 10.1136/bmj.2.6151.1532-a. [DOI] [PMC free article] [PubMed] [Google Scholar]