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. 1976 Aug;26(169):595–598.

Complications of `Slow-K' therapy

Francis Sandor
PMCID: PMC2158348  PMID: 966209

Abstract

(1) The failure of `Slow-K' tablets to disintegrate prevents rapid release but allows them to be trapped by their bulk in the intestine.

(2) Two cases are reported. In the first the tablet was trapped in a caecal diverticulum and the patient developed an abcess. In the second, abdominal pain developed which subsided when `Slow-K' was stopped. Later `Slow-K' was again started and the patient developed dysphagia.

(3) The possibility of abdominal complications with this treatment should be remembered.

(4) Effervescent KC1 preparations may replace `Slow-K' but KC1 supplementation may be necessary only in cardiac disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ashby W. B., Humphreys J., Smith S. J. Small-bowel ulceration induced by potassium chloride. Br Med J. 1965 Dec 11;2(5475):1409–1412. doi: 10.1136/bmj.2.5475.1409. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Dargie H. J., Boddy K., Kennedy A. C., King P. C., Read P. R., Ward D. M. Total body potassium in long-term frusemide therapy: is potassium supplementation necessary? Br Med J. 1974 Nov 9;4(5940):316–319. doi: 10.1136/bmj.4.5940.316. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. De Wardener H. E., Clarkson E. M., Ford J. Potassium supplements. Br Med J. 1969 Oct 18;4(5676):168–168. doi: 10.1136/bmj.4.5676.168-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Edmondson R. P., Thomas R. D., Hilton P. J., Patrick J., Jones N. F. Leucocyte electrolytes in cardiac and non-cardiac patients receiving diuretics. Lancet. 1974 Jan 5;1(7845):12–14. doi: 10.1016/s0140-6736(74)93001-3. [DOI] [PubMed] [Google Scholar]
  5. Howie A. D., Strachan R. W. Slow release potassium chloride treatment. Br Med J. 1975 Apr 26;2(5964):176–176. doi: 10.1136/bmj.2.5964.176. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Lawson D. H. Adverse reactions to potassium chloride. Q J Med. 1974 Jul;43(171):433–440. [PubMed] [Google Scholar]
  7. McAvoy B. R. Letter: Mouth ulceration and slow-release potassium tablets. Br Med J. 1974 Oct 19;4(5937):164–165. doi: 10.1136/bmj.4.5937.164-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Modlin J. F., Herrmann K., Brandling-Bennett A. D., Eddins D. L., Hayden G. F. Risk of congenital abnormality after inadvertent rubella vaccination of pregnant women. N Engl J Med. 1976 Apr 29;294(18):972–974. doi: 10.1056/NEJM197604292941802. [DOI] [PubMed] [Google Scholar]
  9. Nordin B. E., Wilkinson R. Potassium supplements. Br Med J. 1970 Feb 14;1(5693):433–433. doi: 10.1136/bmj.1.5693.433-a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Wilkinson P. R., Issler H., Hesp R., Raftery E. B. Total body and serum potassium during prolonged thiazide therapy for essential hypertension. Lancet. 1975 Apr 5;1(7910):759–762. doi: 10.1016/s0140-6736(75)92432-0. [DOI] [PubMed] [Google Scholar]
  11. Wynn V. Potassium chloride and intestinal ulceration. Lancet. 1965 Dec 11;2(7424):1241–1241. doi: 10.1016/s0140-6736(65)90671-9. [DOI] [PubMed] [Google Scholar]

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