Abstract
D-Galactonate is catabolized in saprophytic mycobacteria to give pyruvate and glyceraldehyde-3-phosphate by a pathway that involves the sequential reactions of galactonate dehydratase, 2-keto-3-deoxy-galactonate kinase, and 6-phospho-2-keto-3-deoxy-galactonate aldolase.
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Selected References
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- CLELAND W. W., KENNEDY E. P. The enzymatic synthesis of psychosine. J Biol Chem. 1960 Jan;235:45–51. [PubMed] [Google Scholar]
- DE LEY J., DOUDOROFF M. The metabolism of D-galactose in Pseudomonas saccharophila. J Biol Chem. 1957 Aug;227(2):745–757. [PubMed] [Google Scholar]
- Deacon J., Cooper R. A. D-Galactonate utilisation by enteric bacteria. The catabolic pathway in Escherichia coli. FEBS Lett. 1977 May 15;77(2):201–205. doi: 10.1016/0014-5793(77)80234-2. [DOI] [PubMed] [Google Scholar]
- Kersters K., De Ley J. D-gluconate dehydratase from Alcaligenes. Methods Enzymol. 1975;42:301–304. doi: 10.1016/0076-6879(75)42131-0. [DOI] [PubMed] [Google Scholar]
- LANNING M. C., COHEN S. S. The detection and estimation of 2-ketohexonic acids. J Biol Chem. 1951 Mar;189(1):109–114. [PubMed] [Google Scholar]
- LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
- MACGEE J., DOUDOROFF M. A new phosphorylated intermediate in glucose oxidation. J Biol Chem. 1954 Oct;210(2):617–626. [PubMed] [Google Scholar]
- Szumilo T., Szymona M. Study on a D-xylose mutant of Mycobacterium sp. 279. Acta Microbiol Pol A. 1971;4(1):113–123. [PubMed] [Google Scholar]
- WEISSBACH A., HURWITZ J. The formation of 2-keto-3-deoxyheptonic acid in extracts of Escherichia coli B. I. Identification. J Biol Chem. 1959 Apr;234(4):705–709. [PubMed] [Google Scholar]
