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. 1979 Dec;140(3):805–808. doi: 10.1128/jb.140.3.805-808.1979

Isolation of temperature-sensitive pantothenate kinase mutants of Salmonella typhimurium and mapping of the coaA gene.

S D Dunn, E E Snell
PMCID: PMC216718  PMID: 230178

Abstract

Temperature-sensitive pantothenate kinase mutants of Salmonella typhimurium LT2 were selected by using the excretion of pantothenate at the nonpermissive temperature as a screening method. Thermolability of the pathothenate kinase activity in extracts of the mutants was demonstrated. The mutations were mapped at min 89 of the Salmonella chromosome, near rpoB, by transduction. As pantothenate kinase catalyzes the first step in the biosynthesis of coenzyme A from pantothenate, the new genetic locus has been designated coaA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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