Abstract
Strains of Lactobacillus casei capable of growing on either ribitol or xylitol carry out a heterolactic fermentation producing ethanol, acetate, and a mixture of D- and L-lactate. Following conversion of the pentitols to ribulose 5-phosphate or xylulose 5-phosphate via enzymatic steps unique to these organisms, the intermediate products are further metabolized by enzymes of the pentose pathway. The initial enzymes of the pathway, i.e., pentitol:phosphoenolypyruvate phosphotransferase and penititol phosphate dehydrogenase, do not appear to be stringently regulated by glucose or intermediate products of glycolysis.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brown A. T., Wittenberger C. L. Fructose-1,6-diphosphate-dependent lactate dehydrogenase from a cariogenic streptococcus: purification and regulatory properties. J Bacteriol. 1972 May;110(2):604–615. doi: 10.1128/jb.110.2.604-615.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brown A. T., Wittenberger C. L. Mannitol and sorbitol catabolism in Streptococcus mutans. Arch Oral Biol. 1973 Jan;18(1):117–126. doi: 10.1016/0003-9969(73)90026-5. [DOI] [PubMed] [Google Scholar]
- HEATH E. C., HURWITZ J., HORECKER B. L., GINSBURG A. Pentose fermentation by Lactobacillus plantarum. I. The cleavage of xylulose 5-phosphate by phosphoketolase. J Biol Chem. 1958 Apr;231(2):1009–1029. [PubMed] [Google Scholar]
- Kornberg H. L. Fine control of sugar uptake by Escherichia coli. Symp Soc Exp Biol. 1973;27:175–193. [PubMed] [Google Scholar]
- LAMPEN J. O., GEST H., SOWDEN J. C. Observations on the mechanism of fermentation of 1-C14-D-xylose by Lactobacillus pentosus. J Bacteriol. 1951 Jan;61(1):97–98. doi: 10.1128/jb.61.1.97-98.1951. [DOI] [PMC free article] [PubMed] [Google Scholar]
- London J., Chace N. M. New pathway for the metabolism of pentitols. Proc Natl Acad Sci U S A. 1977 Oct;74(10):4296–4300. doi: 10.1073/pnas.74.10.4296. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Maryanski J. H., Wittenberger C. L. Mannitol transport in Streptococcus mutans. J Bacteriol. 1975 Dec;124(3):1475–1481. doi: 10.1128/jb.124.3.1475-1481.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McGinnis J. F., Paigen K. Catabolite inhibition: a general phenomenon in the control of carbohydrate utilization. J Bacteriol. 1969 Nov;100(2):902–913. doi: 10.1128/jb.100.2.902-913.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rogosa M., Love L. L. Direct quantitative gas chromatographic separation of C2-C6 fatty acids, methanol, and ethyl alcohol in aqueous microbial fermentation media. Appl Microbiol. 1968 Feb;16(2):285–290. doi: 10.1128/am.16.2.285-290.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stetter K. O., Kandler O. Untersuchungen zur Entstehung von DL-Milchsäure bei Lactobacillen und Charakterisierung einer Milchsäureracemase bei einigen Arten der Untergattung Streptobacterium. Arch Mikrobiol. 1973 Dec 31;94(3):221–247. [PubMed] [Google Scholar]
- WOLIN M. J. FRUCTOSE-1,6-DIPHOSPHATE REQUIREMENT OF STREPTOCOCCAL LACTIC DEHYDROGENASES. Science. 1964 Nov 6;146(3645):775–777. doi: 10.1126/science.146.3645.775. [DOI] [PubMed] [Google Scholar]
- Winkler H. H., Wilson T. H. Inhibition of beta-galactoside transport by substrates of the glucose transport system in Escherichia coli. Biochim Biophys Acta. 1967;135(5):1030–1051. doi: 10.1016/0005-2736(67)90073-9. [DOI] [PubMed] [Google Scholar]
- de Vries W., Kapteijn W. M., van der Beek E. G., Stouthamer A. H. Molar growth yields and fermentation balances of Lactobacillus casei L3 in batch cultures and in continuous cultures. J Gen Microbiol. 1970 Nov;63(3):333–345. doi: 10.1099/00221287-63-3-333. [DOI] [PubMed] [Google Scholar]