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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1997 Sep;63(3):404–407. doi: 10.1136/jnnp.63.3.404

Isolated myoclonic alien hand as the sole presentation of pathologically established Creutzfeldt-Jakob disease: a report of two patients

D MacGowan 1, N Delanty 1, F Petito 1, M Edgar 1, J Mastrianni 1, S DeArmond 1
PMCID: PMC2169703  PMID: 9328266

Abstract

Creutzfeldt-Jakob disease may have many atypical presentations before the development of classic progressive dementia and startle myoclonus. In two patients with pathologically established disease association with a progressive alien hand syndrome was the sole initial manifestation of the disease.



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