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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1998 Jul;65(1):119–121. doi: 10.1136/jnnp.65.1.119

Parkinsonism and dystonia in central pontine and extrapontine myelinolysis

A Seiser 1, S Schwarz 1, M Aichinger-Steiner 1, G Funk 1, P Schnider 1, M Brainin 1
PMCID: PMC2170170  PMID: 9667573

Abstract

Parkinsonism as well as dystonic signs are rarely seen in central pontine myelinolysis and extrapontine myelinolysis. A 51year old woman developed central pontine myelinolysis and extrapontine myelinolysis with parkinsonism after severe vomiting which followed alcohol and drug intake, even though marked hyponatraemia had been corrected gradually over six days. Parkinsonism resolved four months after onset, but she then exhibited persistent retrocollis, spasmodic dysphonia, and focal dystonia of her left hand. Although the medical literature documents three similar patients, this patient is different as dystonic symptoms only developed four months after parkinsonian signs had resolved.



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