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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1998 Oct;65(4):467–471. doi: 10.1136/jnnp.65.4.467

Crime in Huntington's disease: a study of registered offences among patients, relatives, and controls

P Jensen 1, K Fenger 1, T Bolwig 1, S A Sorensen 1
PMCID: PMC2170288  PMID: 9771767

Abstract

OBJECTIVES—Criminal behaviour has been described as a problem in Huntington's disease, but systematic studies including control groups have been missing. Based on information from Danish registries, rates and types of crime committed by patients with Huntington's disease, non-affected relatives, and controls were studied.
METHODS—99 males and 151 females with Huntington's disease were compared with 334 non-affected first degree relatives (134 men and 200 women) and to matched control groups as to frequencies and types of registered criminal convictions. Due to specific age criteria, the group of relatives comprised only about 9% carriers of the gene coding for Huntington's disease.
RESULTS—In male patients, crime rates were significantly increased compared with first degree relatives (RR=2.8) and controls (RR=2.3). All types of crime occurred more often in male patients; more severe crimes (murder, rape, arson) were not reported. Rates of drunken driving were significantly increased compared with relatives (RR=3.8) and controls (RR=7.1). Crime rates were neither increased in female patients nor in male and female first degree relatives.
CONCLUSION—The results indicate increased prevalence of criminal behaviour in males carrying the gene for Huntington's disease. The crimes committed seem to be of relatively minor severity and are probably closely linked to the personality changes often seen as a result of the disease process, although depressive reactions to the disease, with secondary alcohol misuse, may also play a part. Environmental and familial factors shared by patients and non-affected at risk persons seem to be of less aetiological importance.



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Selected References

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  1. Dewhurst K., Oliver J. E., McKnight A. L. Socio-psychiatric consequences of Huntington's disease. Br J Psychiatry. 1970 Mar;116(532):255–258. doi: 10.1192/bjp.116.532.255. [DOI] [PubMed] [Google Scholar]
  2. Folstein S. E., Franz M. L., Jensen B. A., Chase G. A., Folstein M. F. Conduct disorder and affective disorder among the offspring of patients with Huntington's disease. Psychol Med. 1983 Feb;13(1):45–52. doi: 10.1017/s0033291700050054. [DOI] [PubMed] [Google Scholar]
  3. Folstein S., Abbott M. H., Chase G. A., Jensen B. A., Folstein M. F. The association of affective disorder with Huntington's disease in a case series and in families. Psychol Med. 1983 Aug;13(3):537–542. doi: 10.1017/s0033291700047966. [DOI] [PubMed] [Google Scholar]
  4. Harper P. S., Newcombe R. G. Age at onset and life table risks in genetic counselling for Huntington's disease. J Med Genet. 1992 Apr;29(4):239–242. doi: 10.1136/jmg.29.4.239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hayden M. R., Ehrlich R., Parker H., Ferera S. J. Social perspectives in Huntington's chorea. S Afr Med J. 1980 Aug 2;58(5):201–203. [PubMed] [Google Scholar]
  6. Hodgins S., Mednick S. A., Brennan P. A., Schulsinger F., Engberg M. Mental disorder and crime. Evidence from a Danish birth cohort. Arch Gen Psychiatry. 1996 Jun;53(6):489–496. doi: 10.1001/archpsyc.1996.01830060031004. [DOI] [PubMed] [Google Scholar]
  7. Hodgins S. Mental disorder, intellectual deficiency, and crime. Evidence from a birth cohort. Arch Gen Psychiatry. 1992 Jun;49(6):476–483. doi: 10.1001/archpsyc.1992.01820060056009. [DOI] [PubMed] [Google Scholar]
  8. Jensen P., Sørensen S. A., Fenger K., Bolwig T. G. A study of psychiatric morbidity in patients with Huntington's disease, their relatives, and controls. Admissions to psychiatric hospitals in Denmark from 1969 to 1991. Br J Psychiatry. 1993 Dec;163:790–797. doi: 10.1192/bjp.163.6.790. [DOI] [PubMed] [Google Scholar]
  9. King M. Alcohol abuse in Huntington's disease. Psychol Med. 1985 Nov;15(4):815–819. doi: 10.1017/s0033291700005043. [DOI] [PubMed] [Google Scholar]
  10. Lindqvist P., Allebeck P. Schizophrenia and crime. A longitudinal follow-up of 644 schizophrenics in Stockholm. Br J Psychiatry. 1990 Sep;157:345–350. doi: 10.1192/bjp.157.3.345. [DOI] [PubMed] [Google Scholar]
  11. Oliver J. E. Huntington's chorea in Northamptonshire. Br J Psychiatry. 1970 Mar;116(532):241–253. doi: 10.1192/bjp.116.532.241. [DOI] [PubMed] [Google Scholar]
  12. PARKER N. Observations on Huntington's chorea based on a Queensland survey. Med J Aust. 1958 Mar 15;45(11):351–359. doi: 10.5694/j.1326-5377.1958.tb86365.x. [DOI] [PubMed] [Google Scholar]
  13. REED T. E., CHANDLER J. H. Huntington's chorea in Michigan. I. Demography and genetics. Am J Hum Genet. 1958 Jun;10(2):201–225. [PMC free article] [PubMed] [Google Scholar]
  14. Tamir A., Whittier J., Korenyi C. Huntington's chorea: a sex difference in psychopathological symptoms. Dis Nerv Syst. 1969 Feb;30(2):103–103. [PubMed] [Google Scholar]
  15. Wessely S. C., Castle D., Douglas A. J., Taylor P. J. The criminal careers of incident cases of schizophrenia. Psychol Med. 1994 May;24(2):483–502. doi: 10.1017/s0033291700027458. [DOI] [PubMed] [Google Scholar]

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