Abstract
OBJECTIVE—To provide clinically useful vibration threshold normal values. METHODS—The graduated Rydel-Seiffer tuning fork was evaluated in 198 healthy controls and 59 patients with a polyneuropathy. The measures were done in triplicate at four locations: the distal interphalangeal joint of the index finger, ulnar styloid process, interphalangeal joint of the hallux, and internal malleolus. The values obtained with this tuning fork in healthy controls and patients with polyneuropathy were compared with the values of an electronic device, the Vibrameter. RESULTS—Vibration sense was better perceived in the arms compared with the legs. There was a significant age related decline of vibration sense at all locations. The values from the Rydel-Seiffer tuning fork and the Vibrameter were significantly correlated in both groups. The sensitivity of these two instruments for the four sites examined in the polyneuropathy group ranged from 29-76% and 31-73%, respectively and was the highest at the hallux for both instruments. CONCLUSION—This study provides clinical useful normal values of vibration threshold for the Rydel-Seiffer tuning fork. This is a simple and easily applicable instrument that assesses vibration sense semiquantitatively and should therefore have a place in routine neurological examination.
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Selected References
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- Arezzo J. C., Schaumburg H. H. The use of the optacon as a screening device. A new technique for detecting sensory loss in individuals exposed to neurotoxins. J Occup Med. 1980 Jul;22(7):461–464. [PubMed] [Google Scholar]
- Bergin P. S., Bronstein A. M., Murray N. M., Sancovic S., Zeppenfeld D. K. Body sway and vibration perception thresholds in normal aging and in patients with polyneuropathy. J Neurol Neurosurg Psychiatry. 1995 Mar;58(3):335–340. doi: 10.1136/jnnp.58.3.335. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bickerton R. C., Barr G. S. The origin of the tuning fork. J R Soc Med. 1987 Dec;80(12):771–773. doi: 10.1177/014107688708001215. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bloom S., Till S., Sönksen P., Smith S. Use of a biothesiometer to measure individual vibration thresholds and their variation in 519 non-diabetic subjects. Br Med J (Clin Res Ed) 1984 Jun 16;288(6433):1793–1795. doi: 10.1136/bmj.288.6433.1793. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Claus D., Carvalho V. P., Neundörfer B., Blaise J. F. Zur Untersuchung des Vibrationsempfindens. Normalbefunde und methodologische Aspekte. Nervenarzt. 1988 Mar;59(3):138–142. [PubMed] [Google Scholar]
- Crausaz F. M., Clavel S., Liniger C., Albeanu A., Assal J. P. Additional factors associated with plantar ulcers in diabetic neuropathy. Diabet Med. 1988 Nov;5(8):771–775. doi: 10.1111/j.1464-5491.1988.tb01106.x. [DOI] [PubMed] [Google Scholar]
- De Michele G., Filla A., Coppola N., Bisogno A., Trombetta L., Santorelli F., Campanella G. Influence of age, gender, height and education on vibration sense. A study by tuning fork in 192 normal subjects. J Neurol Sci. 1991 Oct;105(2):155–158. doi: 10.1016/0022-510x(91)90139-x. [DOI] [PubMed] [Google Scholar]
- Fagius J., Wahren L. K. Variability of sensory threshold determination in clinical use. J Neurol Sci. 1981 Jul;51(1):11–27. doi: 10.1016/0022-510x(81)90056-3. [DOI] [PubMed] [Google Scholar]
- Goldberg J. M., Lindblom U. Standardised method of determining vibratory perception thresholds for diagnosis and screening in neurological investigation. J Neurol Neurosurg Psychiatry. 1979 Sep;42(9):793–803. doi: 10.1136/jnnp.42.9.793. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Griffin J. W., Watson D. F. Axonal transport in neurological disease. Ann Neurol. 1988 Jan;23(1):3–13. doi: 10.1002/ana.410230103. [DOI] [PubMed] [Google Scholar]
- HOWELL T. H. Senile deterioration of the central nervous system; a clinical study. Br Med J. 1949 Jan 8;1(4592):56–58. doi: 10.1136/bmj.1.4592.56. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hilz M. J., Claus D., Rösl G., Hofmann E., Braun J., Neundörfer B. Besserung des Temperatur- und Vibrationsempfindens bei chronischer Urämie nach Einzeldialyse. Fortschr Neurol Psychiatr. 1995 Jul;63(7):264–269. doi: 10.1055/s-2007-996625. [DOI] [PubMed] [Google Scholar]
- Hilz M. J., Zimmermann P., Rösl G., Scheidler W., Braun J., Stemper B., Neundörfer B. Vibrameter testing facilitates the diagnosis of uremic and alcoholic polyneuropathy. Acta Neurol Scand. 1995 Dec;92(6):486–490. doi: 10.1111/j.1600-0404.1995.tb00485.x. [DOI] [PubMed] [Google Scholar]
- Hotta N., Sugimura K., Tsuchida I., Sano T., Koh N., Matsumae H., Sakamoto N. Use of the C64 quantitative tuning fork and the effect of niceritrol in diabetic neuropathy. Clin Ther. 1994 Nov-Dec;16(6):1007–1015. [PubMed] [Google Scholar]
- Kokmen E., Bossemeyer R. W., Jr, Barney J., Williams W. J. Neurological manifestations of aging. J Gerontol. 1977 Jul;32(4):411–419. doi: 10.1093/geronj/32.4.411. [DOI] [PubMed] [Google Scholar]
- Liniger C., Albeanu A., Bloise D., Assal J. P. The tuning fork revisited. Diabet Med. 1990 Dec;7(10):859–864. doi: 10.1111/j.1464-5491.1990.tb01319.x. [DOI] [PubMed] [Google Scholar]
- Merchut M. P., Toleikis S. C. Aging and quantitative sensory thresholds. Electromyogr Clin Neurophysiol. 1990 Aug-Sep;30(5):293–297. [PubMed] [Google Scholar]
- STEINBERG F. U., GRABER A. L. THE EFFECT OF AGE AND PERIPHERAL CIRCULATION ON THE PERCEPTION OF VIBRATION. Arch Phys Med Rehabil. 1963 Dec;44:645–650. [PubMed] [Google Scholar]
- Thivolet C., el Farkh J., Petiot A., Simonet C., Tourniaire J. Measuring vibration sensations with graduated tuning fork. Simple and reliable means to detect diabetic patients at risk of neuropathic foot ulceration. Diabetes Care. 1990 Oct;13(10):1077–1080. doi: 10.2337/diacare.13.10.1077. [DOI] [PubMed] [Google Scholar]
- Thomson F. J., Masson E. A., Boulton A. J. The clinical diagnosis of sensory neuropathy in elderly people. Diabet Med. 1993 Nov;10(9):843–846. doi: 10.1111/j.1464-5491.1993.tb00177.x. [DOI] [PubMed] [Google Scholar]
- Wiles P. G., Pearce S. M., Rice P. J., Mitchell J. M. Vibration perception threshold: influence of age, height, sex, and smoking, and calculation of accurate centile values. Diabet Med. 1991 Feb-Mar;8(2):157–161. doi: 10.1111/j.1464-5491.1991.tb01563.x. [DOI] [PubMed] [Google Scholar]