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. 1981 Apr;146(1):41–48. doi: 10.1128/jb.146.1.41-48.1981

Mitomycin C-induced synthesis of cloacin DF13 and lethality in cloacinogenic Escherichia coli cells.

G J van Tiel-Menkveld, E Veltkamp, F K De Graaf
PMCID: PMC217049  PMID: 7012123

Abstract

Treatment of cloacinogenic cultures with increasing concentrations of mitomycin C induced an increasing synthesis of cloacin DF13 accompanied by a decreasing number of colony-forming cells. Cells grown in the presence of glucose required a 10-fold-higher concentration of mitomycin C for optimal induction of cloacin production than did cells grown with lactate. Release of the cloacin was hampered in glucose-grown cells. Experiments with various CloDF13 insertion and deletion mutants revealed that the transcription of CloDF13 deoxyribonucleic acid sequences adjacent to the cloacin structural gene was essential for mitomycin C-induced lethality.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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