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. 1981 Apr;146(1):418–421. doi: 10.1128/jb.146.1.418-421.1981

Deoxyribonucleic acid initiation mutation dnaB252 is suppressed by elevated dnaC+ gene dosage.

R A Sclafani, J A Wechsler
PMCID: PMC217101  PMID: 7012124

Abstract

The Escherichia coli dnaB252 allele is the only dnaB mutation which confers a deoxyribonucleic acid initiation-defective phenotype on the cell. The presence of a multicopy hybrid plasmid containing the dnaC+ gene in a dnaB252 strain completely suppressed the temperature-sensitive phenotype. It is suggested that at high temperature the dnaB252 protein has a lowered affinity for dnaC protein, and that the formation of a dnaB-dnaC complex is mandatory for initiation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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