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. 1981 Mar;145(3):1452–1455. doi: 10.1128/jb.145.3.1452-1455.1981

Regulation of dimorphism in Histoplasma capsulatum by cyclic adenosine 3',5'-monophosphate.

J Medoff, E Jacobson, G Medoff
PMCID: PMC217157  PMID: 6259135

Abstract

During temperature-induced transition of the dimorphic pathogenic fungus Histoplasma capsulatum from the single yeast cell form to the multicellular mycelial form, there was an increase in intracellular cyclic adenosine 3',5'-monophosphate (cAMP) levels as well as a striking accumulation of cAMP in the medium. cAMP levels also changed during the reverse mycelium-to-yeast transition.

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Selected References

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